AZD3229
AZD3229 is a highly effective small molecule inhibitor targeting diverse KIT mutations, demonstrating potent anti-proliferative activity in the low nanomolar range against gastrointestinal stromal tumor (GIST) cell lines. It is a valuable research tool for investigating KIT-driven oncogenesis in both in vitro and in vivo preclinical models.
Product Specifications
CAS Number
2248003-60-1
Product Name Alternative
Inhibit, Inhibitor, Kit, AZD 3229, AZD3229, AZD-3229, CD117, cKit, c-Kit, SCFR
Field of Research
Signal Transduction
Purity
98.83% (May vary between batches)
Solubility
H2O:Insoluble; DMSO:95 mg/mL (198.12 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (10.43 mM)
Smiles
COCCOc1cc (F) c2c (Nc3ccc (NC (=O) Cn4cc (nn4) C (C) C) cc3) ncnc2c1
Molecular Formula
C24H26FN7O3
Molecular Weight
479.51
Storage Conditions
-20°C
Notes
For research use only.
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