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AZD3229

AZD3229 is a highly effective small molecule inhibitor targeting diverse KIT mutations, demonstrating potent anti-proliferative activity in the low nanomolar range against gastrointestinal stromal tumor (GIST) cell lines. It is a valuable research tool for investigating KIT-driven oncogenesis in both in vitro and in vivo preclinical models.

Product Specifications

CAS Number

2248003-60-1

Product Name Alternative

Inhibit, Inhibitor, Kit, AZD 3229, AZD3229, AZD-3229, CD117, cKit, c-Kit, SCFR

Field of Research

Signal Transduction

Purity

98.83% (May vary between batches)

Solubility

H2O:Insoluble; DMSO:95 mg/mL (198.12 mM) ;10% DMSO+90% Corn Oil:5 mg/mL (10.43 mM)

Smiles

COCCOc1cc (F) c2c (Nc3ccc (NC (=O) Cn4cc (nn4) C (C) C) cc3) ncnc2c1

Molecular Formula

C24H26FN7O3

Molecular Weight

479.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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