INCB-057643
INCB057643 is a potent, selective, and orally available small molecule inhibitor of BET proteins. It is utilized in oncology research to investigate epigenetic mechanisms in cancers such as AML and solid tumors, demonstrating activity in both cellular and animal models.
Product Specifications
CAS Number
1820889-23-3
Product Name Alternative
INCB057643, INCB-057643, INCB 057643, inhibit, EpigeneticReaderDomain, Epigenetic Reader Domain, Inhibitor, Apoptosis, BET
Field of Research
Cell Biology, Epigenetics & Chromatin
Purity
99.50% (May vary between batches)
Solubility
DMSO:65 mg/mL (156.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM)
Smiles
CN1C (=O) C (C) (C) Oc2c1cc (cc2-c1cn (C) c (=O) c2[nH]ccc12) S (C) (=O) =O
Molecular Formula
C20H21N3O5S
Molecular Weight
415.46
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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