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INCB-057643

INCB057643 is a potent, selective, and orally available small molecule inhibitor of BET proteins. It is utilized in oncology research to investigate epigenetic mechanisms in cancers such as AML and solid tumors, demonstrating activity in both cellular and animal models.

Product Specifications

CAS Number

1820889-23-3

Product Name Alternative

INCB057643, INCB-057643, INCB 057643, inhibit, EpigeneticReaderDomain, Epigenetic Reader Domain, Inhibitor, Apoptosis, BET

Field of Research

Cell Biology, Epigenetics & Chromatin

Purity

99.50% (May vary between batches)

Solubility

DMSO:65 mg/mL (156.45 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.81 mM)

Smiles

CN1C (=O) C (C) (C) Oc2c1cc (cc2-c1cn (C) c (=O) c2[nH]ccc12) S (C) (=O) =O

Molecular Formula

C20H21N3O5S

Molecular Weight

415.46

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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