Cycloguanil hydrochloride
Cycloguanil hydrochloride is the active metabolite of the antimalarial proguanil, functioning as a potent dihydrofolate reductase inhibitor with selectivity for the Plasmodium enzyme. It is widely used in antimalarial research for both in vitro enzymatic assays and in vivo efficacy studies in animal models of malaria.
Product Specifications
CAS Number
152-53-4
Product Name Alternative
Parasite, inhibit, Inhibitor, Chloroguanide Triazine, Cycloguanil, Cycloguanil Hydrochloride, Cycloguanil hydrochloride, DrugMetabolite, Drug Metabolite
Field of Research
Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery
Purity
98.72% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.94 mM) ; DMSO:20 mg/mL (69.4 mM) ; H2O:5 mg/mL (17.35 mM)
Smiles
Cl.CC1 (C) N=C (N) N=C (N) N1c1ccc (Cl) cc1
Molecular Formula
C11H14ClN5.ClH
Molecular Weight
288.18
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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