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Cycloguanil hydrochloride

Cycloguanil hydrochloride is the active metabolite of the antimalarial proguanil, functioning as a potent dihydrofolate reductase inhibitor with selectivity for the Plasmodium enzyme. It is widely used in antimalarial research for both in vitro enzymatic assays and in vivo efficacy studies in animal models of malaria.

Product Specifications

CAS Number

152-53-4

Product Name Alternative

Parasite, inhibit, Inhibitor, Chloroguanide Triazine, Cycloguanil, Cycloguanil Hydrochloride, Cycloguanil hydrochloride, DrugMetabolite, Drug Metabolite

Field of Research

Infectious Disease & Virology, Metabolism Research, Pharmacology & Drug Discovery

Purity

98.72% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.94 mM) ; DMSO:20 mg/mL (69.4 mM) ; H2O:5 mg/mL (17.35 mM)

Smiles

Cl.CC1 (C) N=C (N) N=C (N) N1c1ccc (Cl) cc1

Molecular Formula

C11H14ClN5.ClH

Molecular Weight

288.18

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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