Cruzain-IN-1
Cruzain-IN-1 (ML092) is a potent, reversible covalent inhibitor of the cysteine protease Cruzain, exhibiting an IC50 of 10 nM. It serves as a valuable biochemical tool for in vitro enzyme inhibition studies and as a lead compound in parasitology research targeting Trypanosoma cruzi, the causative agent of Chagas disease.
Product Specifications
CAS Number
1199523-24-4
Product Name Alternative
Cruzain IN 1, CruzainIN1, Cruzain-IN-1, Inhibitor, ML 092, ML092, ML-092, inhibit, Trypanosoma cruzi
Field of Research
Infectious Disease & Virology
Purity
99.25% (May vary between batches)
Solubility
DMSO:45 mg/mL (149.87 mM)
Smiles
CCn1cnc2c (Nc3cc (F) cc (F) c3) nc (nc12) C#N
Molecular Formula
C14H10F2N6
Molecular Weight
300.27
Storage Conditions
-20°C
Notes
For research use only.
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