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TCS-OX2-29

TCS-OX2-29 is a highly selective orexin receptor 2 (OX2R) antagonist with an IC50 of 40 nM, showing over 250-fold selectivity versus the OX1 receptor. This tool compound is valuable for in vitro and in vivo research exploring the physiological roles of orexin signaling in sleep, arousal, and neuropsychiatric disorders.

Product Specifications

CAS Number

372523-75-6

Product Name Alternative

TCS OX2 29, TCS-OX-2-29, TCS-OX2-29, TCSOX229, inhibit, Orexin Receptor (OX Receptor), OXReceptor, OX2, OX Receptor, Hypocretin Receptor, HCRT Receptor, Inhibitor

Field of Research

Neuroscience, Pharmacology & Drug Discovery

Purity

99.08% (May vary between batches)

Solubility

DMSO:9 mg/mL (22.64 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.52 mM)

Smiles

COc1cc2CCN (Cc2cc1OC) C (=O) [C@@H] (NCc1ccncc1) C (C) (C) C

Molecular Formula

C23H31N3O3

Molecular Weight

397.51

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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