Retapamulin
Retapamulin (SB-275833) is a potent pleuromutilin antibiotic that binds with high affinity (Kd ~3 nM) to the ribosomes of both Gram-positive and Gram-negative bacteria like S. aureus and E. coli. It is a valuable tool for studying bacterial protein synthesis inhibition in vitro and has demonstrated efficacy in models of topical skin infection.
Product Specifications
CAS Number
224452-66-8
Product Name Alternative
Inhibit, Inhibitor, Antibiotic, Bacterial, ribosome, Retapamulin, SB 275833, SB275833, SB-275833
Field of Research
Infectious Disease & Virology, Pharmacology & Drug Discovery
Purity
99.57% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:104 mg/mL (200.87 mM) ; DMSO:18.33 mg/mL (35.4 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.86 mM)
Smiles
CC1CCC23CCC (=O) C2C1 (C) C (CC (C) (C=C) C (O) C3C) OC (=O) CSC1CC2CCC (C1) N2C
Molecular Formula
C30H47NO4S
Molecular Weight
517.76
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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