Rotundine
Rotundine (L-THP, Gindarine) is a selective dopamine D1 receptor antagonist with an IC50 of 166 nM. It is widely used in neuroscience research to study dopaminergic pathways, with applications in both in vitro binding assays and in vivo behavioral models.
Product Specifications
CAS Number
483-14-7
Product Name Alternative
5-HT1A, 5-HT Receptor, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, (-) -Tetrahydropalmatine, Dopamine, DopamineReceptor, Dopamine Receptor, D1, D2, D3, Caseanine, Gindarine, inhibit, Inhibitor, L-Tetrahydropalmatine, Serotonin Receptor, Rotundine, Tetrahydropalmatine
Field of Research
Neuroscience, Pharmacology & Drug Discovery
Purity
99.73% (May vary between batches)
Solubility
Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:55 mg/mL (154.74 mM)
Smiles
O (C) C=1C=C2[C@]3 (N (CC=4C (C3) =CC=C (OC) C4OC) CCC2=CC1OC) [H]
Molecular Formula
C21H25NO4
Molecular Weight
355.43
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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