Safinamide mesylate
Safinamide mesylate is a potent, reversible, and highly selective monoamine oxidase B (MAO-B) inhibitor, exhibiting an IC50 of 98 nM and >5,900-fold selectivity over MAO-A. It is widely used in research for investigating Parkinson's disease mechanisms and neuroprotection in both cellular and animal models.
Product Specifications
CAS Number
202825-46-5
Product Name Alternative
Deprivation/reperfusion, EMD1195686, EMD-1195686, EMD1195686 Mesylate, EMD-1195686 Mesylate, EMD 1195686, EMD 1195686 mesylate, FCE26743, FCE-26743, FCE28073 mesylate, FCE 26743, Glucose, MonoamineOxidase, Monoamine Oxidase, MAO, PNU-151774E, FCE 28073, PNU-151774E, FCE-28073, OGD/R, NW1015, NW 1015, neurorescuing, Parkinson, Stroke, Safinamide, α-aminoamide derivative
Field of Research
Metabolism Research, Neuroscience, Pharmacology & Drug Discovery
Purity
98.41% (May vary between batches)
Solubility
H2O:73 mg/mL (183.21 mM) ; DMSO:40 mg/mL (100.39 mM) ; Ethanol:11 mg/mL (27.61 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.02 mM)
Smiles
CS (O) (=O) =O.C[C@H] (NCc1ccc (OCc2cccc (F) c2) cc1) C (N) =O
Molecular Formula
C18H23FN2O5S
Molecular Weight
398.45
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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