SGC-CBP30
SGC-CBP30 is a potent and selective small molecule inhibitor of the CREBBP and EP300 bromodomains, with IC50 values of 21 nM and 38 nM, respectively. It is a valuable chemical probe for epigenetic research, used in vitro to investigate the roles of these acetyl-lysine readers in gene regulation, cellular differentiation, and disease models.
Product Specifications
CAS Number
1613695-14-9
Product Name Alternative
CREBBP, cells, BRD, ankylosing, anti-inflammatory, arthritis, Inhibitor, HAT, HATs, Histone Acetyltransferase, HistoneAcetyltransferase, EP300, Epigenetic Reader Domain, epigenetic, EpigeneticReaderDomain, inhibit, IL-17A, SGC-CBP30, SGC-CBP-30, SGCCBP30, SGC CBP30, psoriatic, spondylitis, Th17
Field of Research
Epigenetics & Chromatin, Immunology & Inflammation
Purity
98.64% (May vary between batches)
Solubility
DMSO:247.5 mg/mL (486.21 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.48 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:93 mg/mL (182.7 mM)
Smiles
COc1ccc (CCc2nc3cc (ccc3n2C[C@H] (C) N2CCOCC2) -c2c (C) noc2C) cc1Cl
Molecular Formula
C28H33ClN4O3
Molecular Weight
509.04
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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