Sirtinol
Sirtinol is a cell-permeable inhibitor that selectively targets SIRT1 and SIRT2 with IC50 values of 131 μM and 38 μM, respectively. It is widely used in research to study the roles of sirtuins in aging, metabolism, and cancer, employing both in vitro cellular assays and in vivo animal models.
Product Specifications
CAS Number
410536-97-9
Product Name Alternative
Inhibit, Inhibitor, Autophagy, Apoptosis, Sirtinol, SIRT2, SIRT1, Sirtuin
Field of Research
Epigenetics & Chromatin, Neuroscience, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
SIRT inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 35 mg/ml) or in Ethanol (up to 10 mg/ml) . Do not store solutions.
Smiles
CC (NC (=O) C1=C (C=CC=C1) \N=C\C1=C (O) C=CC2=CC=CC=C12) C1=CC=CC=C1
Molecular Formula
C26H22N2O2
Molecular Weight
394.5
Storage Conditions
-20°C / protect from light
Notes
For research use only.
Other Product Names
2-[ (2-Hydroxynaphthalen-1-ylmethylene) amino]-N- (1-phenethyl) benzamide
Available Sizes
Frequently Asked Questions
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