Sitaxsentan sodium
Sitaxsentan sodium (TBC11251 sodium salt) is a potent and highly selective endothelin A (ETA) receptor antagonist. It is a valuable research tool for investigating the role of endothelin-1 signaling in cardiovascular diseases, pulmonary hypertension, and cancer, both in cellular and animal models.
Product Specifications
CAS Number
210421-74-2
Product Name Alternative
IPI 1040, IPI-1040, IPI1040, inhibit, Inhibitor, Endothelin Receptor, EndothelinReceptor, ET-A, TBC11251 sodium, TBC11251 sodium salt, TBC-11251, TBC 11251, TBC11251, Thelin, Sitaxsentan sodium, Sitaxentan sodium, Sitaxsentan
Field of Research
Pharmacology & Drug Discovery
Purity
≥95% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:60 mg/mL (125.82 mM) ; Ethanol:20 mg/mL (41.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.19 mM)
Smiles
[Na+].Cc1noc ([N-]S (=O) (=O) c2ccsc2C (=O) Cc2cc3OCOc3cc2C) c1Cl
Molecular Formula
C18H14ClN2O6S2·Na
Molecular Weight
476.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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