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Sofosbuvir

Sofosbuvir is a small molecule antiviral prodrug, metabolized to an active uridine analog that potently inhibits the HCV NS5B RNA-dependent RNA polymerase. It is a key research tool for studying HCV replication mechanisms and evaluating antiviral efficacy in both cellular and animal models of hepatitis C infection.

Product Specifications

CAS Number

1190307-88-0

Product Name Alternative

Sofosbuvir, PSI 7977, PSI7977, PSI-7977, Inhibitor, HCV Protease, HCV, Hepatitis C virus, HCVProtease, GS7977, GS-7977, GS 7977, inhibit

Field of Research

Infectious Disease & Virology, Pharmacology & Drug Discovery, Protein Biochemistry

Purity

99.77% (May vary between batches)

Solubility

Ethanol:93 mg/mL (175.65 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (1.89 mM) ; DMSO:250 mg/mL (472.19 mM) ; H2O:9 mg/mL (17 mM)

Smiles

CC (C) OC (=O) [C@H] (C) NP (=O) (OC[C@H]1O[C@@H] (n2ccc (=O) [nH]c2=O) [C@] (C) (F) [C@@H]1O) Oc1ccccc1

Molecular Formula

C22H29FN3O9P

Molecular Weight

529.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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