STF-62247
STF-62247 is a potent TGN inhibitor, demonstrating differential activity with IC50 values of 0.625 μM in RCC4 cells and 16 μM in RCC4/VHL cells. This small molecule is a valuable research tool for investigating autophagy, cellular stress responses, and VHL-dependent pathways in cancer models, both in vitro and in vivo.
Product Specifications
CAS Number
315702-99-9
Product Name Alternative
Cell, cytotoxic, carcinoma, Autophagy, Inhibitor, Estrogen Receptor, EstrogenReceptor, ER, inhibit, intracytoplasmic, RCC, progestogenReceptor, progestogen Receptor, renal, STF 62247, STF62247, STF-62247, vacuoles, VHL
Field of Research
Cell Biology, Metabolism Research
Purity
99.30% (May vary between batches)
Solubility
Ethanol:3 mg/mL (11.22 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (7.48 mM) ; DMSO:55 mg/mL (205.72 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cc1cccc (Nc2nc (cs2) -c2ccncc2) c1
Molecular Formula
C15H13N3S
Molecular Weight
267.35
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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