T0901317
T0901317 is a dual agonist of LXR and FXR with EC50 values of approximately 50 nM and 5 μM, respectively. It also acts as an inhibitor of NF-κB. This small molecule is a valuable research tool for studying nuclear receptor signaling and inflammation in metabolic and liver disease models, both in vitro and in vivo.
Product Specifications
CAS Number
293754-55-9
Product Name Alternative
LDL, HS-68, Inhibitor, FXR, fibroblasts, foreskin, orally, ovarian, LXR, LXRα, LXRβ, inhibit, Liver X Receptor, LiverXReceptor, Liver X receptor, NR1H4, CaOV3, carcinoma, atherosclerosis, Apoptosis, A2780, RAR-related orphan receptor, SKOV3, T0901317, T-0901317, T 0901317, RORα, RORγ, ROR
Field of Research
Cell Biology, Neuroscience
Purity
>98%
Form
Powder
Solubility
Soluble in DMSO (up to 50 mg/ml) or in ethanol (up to 50 mg/ml)
Smiles
C (C (F) (F) F) (C (F) (F) F) (O) C1=CC=C (N (S (=O) (=O) C2=CC=CC=C2) CC (F) (F) F) C=C1
Molecular Formula
C17H12F9NO3S
Molecular Weight
481.3
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
N- (2,2,2-Trifluoroethyl) -N-[4-[2,2,2-trifluoro-1-hydroxy-1- (trifluoromethyl) ethyl]phenyl]-benzenesulfonamide
Available Sizes
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