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TIC10 Isomer

TIC10 Isomer (ONC201 isomer) is a structural analog with enhanced pharmaceutical properties, including blood-brain barrier penetration and pharmacokinetic stability. It acts by inactivating Akt and ERK to upregulate TRAIL via Foxo3a, supporting its investigation in preclinical oncology research, including in vivo models for solid tumors and glioblastoma.

Product Specifications

CAS Number

41276-02-2

Product Name Alternative

ONC201 isomer, Inhibitor, inhibit, TRAIL, TIC10 Analogue, TIC10 Isomer, TIC-10 Isomer

Purity

99.25% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.29 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:9 mg/mL (23.29 mM)

Smiles

Cc1ccccc1CN1C2=NCCN2C (=O) C2=C1CCN (Cc1ccccc1) C2

Molecular Formula

C24H26N4O

Molecular Weight

386.49

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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