TIC10 Isomer
TIC10 Isomer (ONC201 isomer) is a structural analog with enhanced pharmaceutical properties, including blood-brain barrier penetration and pharmacokinetic stability. It acts by inactivating Akt and ERK to upregulate TRAIL via Foxo3a, supporting its investigation in preclinical oncology research, including in vivo models for solid tumors and glioblastoma.
Product Specifications
CAS Number
41276-02-2
Product Name Alternative
ONC201 isomer, Inhibitor, inhibit, TRAIL, TIC10 Analogue, TIC10 Isomer, TIC-10 Isomer
Purity
99.25% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:0.5 mg/mL (1.29 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:9 mg/mL (23.29 mM)
Smiles
Cc1ccccc1CN1C2=NCCN2C (=O) C2=C1CCN (Cc1ccccc1) C2
Molecular Formula
C24H26N4O
Molecular Weight
386.49
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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