VU0364770
VU0364770 is a selective positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 1.1 μM, demonstrating negligible activity at 68 other tested receptors. This selectivity makes it a valuable research tool for investigating mGlu4's role in neurological disorders, including Parkinson's disease, in both in vitro and in vivo models.
Product Specifications
CAS Number
61350-00-3
Product Name Alternative
Inhibitor, inhibit, mGluR, mGluR4, Metabotropic glutamate receptors, VU0364770, VU-0364770, VU 0364770
Field of Research
Neuroscience
Purity
99.65% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.6 mM) ; DMSO:50 mg/mL (214.9 mM)
Smiles
Clc1cccc (NC (=O) c2ccccn2) c1
Molecular Formula
C12H9ClN2O
Molecular Weight
232.67
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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