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VU0364770

VU0364770 is a selective positive allosteric modulator (PAM) of the mGlu4 receptor with an EC50 of 1.1 μM, demonstrating negligible activity at 68 other tested receptors. This selectivity makes it a valuable research tool for investigating mGlu4's role in neurological disorders, including Parkinson's disease, in both in vitro and in vivo models.

Product Specifications

CAS Number

61350-00-3

Product Name Alternative

Inhibitor, inhibit, mGluR, mGluR4, Metabotropic glutamate receptors, VU0364770, VU-0364770, VU 0364770

Field of Research

Neuroscience

Purity

99.65% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.6 mM) ; DMSO:50 mg/mL (214.9 mM)

Smiles

Clc1cccc (NC (=O) c2ccccn2) c1

Molecular Formula

C12H9ClN2O

Molecular Weight

232.67

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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