AMG319
AMG319 is a potent and selective PI3Kδ inhibitor (IC50 = 18 nM) with >47-fold selectivity against other PI3K isoforms. This compound has been utilized in Phase 2 clinical studies and preclinical research for investigating hematological malignancies and immune disorders in both cellular and animal models.
Product Specifications
CAS Number
1608125-21-8
Product Name Alternative
PI3K, PI3Kβ, PI3Kα, PI3Kγ, PI3Kδ, Phosphoinositide 3-kinase, Inhibitor, inhibit, AMG319, AMG-319, AMG 319
Field of Research
Signal Transduction
Purity
98.57% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.19 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:71 mg/mL (184.22 mM) ; Ethanol:71 mg/mL (184.22 mM)
Smiles
C[C@H] (Nc1ncnc2[nH]cnc12) c1cc2ccc (F) cc2nc1-c1ccccn1
Molecular Formula
C21H16FN7
Molecular Weight
385.4
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
