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AP-III-a4

ENOblock is a potent, first-in-class nonsubstrate analogue inhibitor of enolase, exhibiting an IC50 of 0.576 μM. It is widely used in biochemical and cancer metabolism research, with applications in both in vitro enzymatic assays and in vivo studies exploring tumor growth inhibition.

Product Specifications

CAS Number

1177827-73-4

Product Name Alternative

Apoptosis, AP III a4, APIIIa4, AP-III-a4, AP-III-a-4, anticancer, antidiabetic, inhibit, Inhibitor, Huh7, enolase, Enolase, ENOblock, HEK, HCT116, zebrafish, Phosphopyruvate hydratase

Field of Research

Cell Biology, Metabolism Research

Purity

98.24% (May vary between batches)

Solubility

H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:5 mg/mL (8.41 mM) ; DMSO:257.5 mg/mL (432.98 mM)

Smiles

NCCOCCOCCNC (=O) Cc1ccc (Nc2nc (NCC3CCCCC3) nc (NCc3ccc (F) cc3) n2) cc1

Molecular Formula

C31H43FN8O3

Molecular Weight

594.72

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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