APS-2-79 hydrochloride
APS-2-79 HCl is a small molecule MAPK pathway antagonist that disrupts RAF dimerization and the conformational activation of KSR-bound MEK. It is a valuable research tool for studying oncogenic RAS/MAPK signaling in both cellular and animal models of cancer and developmental disorders.
Product Specifications
CAS Number
2002381-31-7
Product Name Alternative
APS 2 79 hydrochloride, APS-2-79 HCl, APS279 hydrochloride, APS-2-79 Hydrochloride, MAP2K, MAPKK, MEK, KSR2, Mitogen-activated protein kinase kinase
Field of Research
Signal Transduction
Purity
97.08% (May vary between batches)
Solubility
DMSO:90 mg/mL (212.32 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:30 mg/mL (70.77 mM)
Smiles
Cl.COc1cc2ncnc (Nc3ccc (Oc4ccccc4) cc3C) c2cc1OC
Molecular Formula
C23H21N3O3·HCl
Molecular Weight
423.89
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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