BDA-366
BDA-366 is a high-affinity, selective antagonist of the Bcl-2 BH4 domain (Ki = 3.3 nM) . It induces a pro-apoptotic conformational change, effectively inhibiting lung cancer cell growth in vitro, and shows potential for apoptosis research in oncology.
Product Specifications
CAS Number
1909226-00-1
Product Name Alternative
Bcl2-BH4 domain, Bcl-2 Family, BDA-366, BDA366, BDA 366, Anticancer, Antiapoptotic function, Antitumor, Lung cancer, Inhibitor, inhibit
Field of Research
Cell Biology
Purity
98.61% (May vary between batches)
Solubility
Ethanol:5 mg/mL (11.81 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween-80+45% Saline:3.3 mg/mL (7.79 mM) ; DMSO:78 mg/mL (184.18 mM)
Smiles
N (C[C@H]1CO1) C2=C3C (=C (NC[C@@H] (CN (CC) CC) O) C=C2) C (=O) C=4C (C3=O) =CC=CC4
Molecular Formula
C24H29N3O4
Molecular Weight
423.5
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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