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BI-78D3

BI-78D3 is a potent and selective competitive inhibitor of JNK with an IC50 of 280 nM. It exhibits over 100-fold selectivity against p38α and shows no activity toward mTOR or PI3K. This compound is a valuable research tool for studying JNK signaling in cellular models of inflammation, apoptosis, and metabolic disease.

Product Specifications

CAS Number

883065-90-5

Product Name Alternative

Inhibit, JNK, Inhibitor, BI78D3, BI-78D3, BI-78D-3, BI 78D3

Field of Research

Signal Transduction

Purity

97.89% (May vary between batches)

Solubility

Ethanol:1.9 mg/mL (5.01 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.27 mM) ; DMSO:37.9 mg/mL (99.9 mM)

Smiles

[O-][N+] (=O) c1cnc (Sc2n[nH]c (=O) n2-c2ccc3OCCOc3c2) s1

Molecular Formula

C13H9N5O5S2

Molecular Weight

379.37

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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