BI-847325
BI-847325 is a potent small molecule that selectively inhibits both MEK2 and Aurora Kinase C with IC50 values of 4 nM and 15 nM, respectively. It is utilized in cancer research to study pathway signaling and has demonstrated antitumor activity in both cellular assays and in vivo xenograft models.
Product Specifications
CAS Number
1207293-36-4
Product Name Alternative
Apoptosis, AuroraKinase, Aurora Kinase, Aurora B (Xenopus laevis), Aurora C (Human), Aurora A (Human), BI847325, BI-847325, BI 847325, MAPKK, MAP2K, MEK, MEK1, MEK2, Inhibitor, Mitogen-activated protein kinase kinase, inhibit
Field of Research
Cell Biology, Epigenetics & Chromatin, Signal Transduction
Purity
95.22% (May vary between batches)
Solubility
Ethanol:1 mg/mL (2.15 mM) ; DMSO:18 mg/mL (38.75 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.15 mM)
Smiles
CCNC (=O) C#Cc1ccc2\C (=C (\Nc3ccc (CN (C) C) cc3) c3ccccc3) C (=O) Nc2c1
Molecular Formula
C29H28N4O2
Molecular Weight
464.56
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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