BIO-acetoxime
BIO-acetoxime (GSK-3 Inhibitor X) is a highly potent and selective dual inhibitor of GSK3α and GSK3β, exhibiting an IC50 of 10 nM. It demonstrates significant selectivity, being over 240-fold more potent against GSK3 than against related kinases CDK5/p25, CDK2/cyclin A, and CDK1/cyclin B. This inhibitor is a valuable research tool for studying GSK3 signaling in neurological disorders and cellular models both in vitro and in vivo.
Product Specifications
CAS Number
667463-85-6
Product Name Alternative
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.15% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.51 mM) ; DMSO:8 mg/mL (20.09 mM)
Smiles
CC (=O) O\N=C1\C (\Nc2ccccc\12) =C1\C (=O) Nc2cc (Br) ccc12
Molecular Formula
C18H12BrN3O3
Molecular Weight
398.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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