BIO-acetoxime
BIO-acetoxime (GSK-3 Inhibitor X) is a highly potent and selective dual inhibitor of GSK3α and GSK3β, exhibiting an IC50 of 10 nM. It demonstrates significant selectivity, being over 240-fold more potent against GSK3 than against related kinases CDK5/p25, CDK2/cyclin A, and CDK1/cyclin B. This inhibitor is a valuable research tool for studying GSK3 signaling in neurological disorders and cellular models both in vitro and in vivo.
Product Specifications
CAS Number
667463-85-6
Product Name Alternative
Field of Research
Cell Biology, Infectious Disease & Virology, Signal Transduction, Stem Cell & Developmental Biology
Purity
97.15% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.51 mM) ; DMSO:8 mg/mL (20.09 mM)
Smiles
CC (=O) O\N=C1\C (\Nc2ccccc\12) =C1\C (=O) Nc2cc (Br) ccc12
Molecular Formula
C18H12BrN3O3
Molecular Weight
398.21
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
Explore Other Products
Browse additional items from our catalog
GRM1 (Metabotropic Glutamate Receptor 1, mGluR1, GPRC1A, MGLUR1) (MaxLight 405) discontinued
Rabbit anti-Encephalitozoon cuniculi (strain GB-M1)(Microsporidian parasite) KIN28 Polyclonal Antibody
LRRTM3 Polyclonal Antibody, AbBy Fluor™ 488 Conjugated
