CPI-169 racemate
CPI-169 is a highly potent and selective inhibitor of EZH2, demonstrating IC50 values of 0.24 nM for wild-type, 0.51 nM for the Y641N mutant, and 6.1 nM for EZH1. This compound is a valuable chemical probe for epigenetic research, enabling the study of histone methylation roles in cancer biology and other diseases in both cellular and animal models.
Product Specifications
CAS Number
1450655-76-1
Product Name Alternative
Field of Research
Epigenetics & Chromatin
Purity
99.14% (May vary between batches)
Solubility
Ethanol:93 mg/mL (175.92 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (175.92 mM)
Smiles
CCS (=O) (=O) N1CCC (CC1) C (C) n1c (C) c (C (=O) NCc2c (OC) cc (C) [nH]c2=O) c2ccccc12
Molecular Formula
C27H36N4O5S
Molecular Weight
528.66
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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