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CPI-169 racemate

CPI-169 is a highly potent and selective inhibitor of EZH2, demonstrating IC50 values of 0.24 nM for wild-type, 0.51 nM for the Y641N mutant, and 6.1 nM for EZH1. This compound is a valuable chemical probe for epigenetic research, enabling the study of histone methylation roles in cancer biology and other diseases in both cellular and animal models.

Product Specifications

CAS Number

1450655-76-1

Product Name Alternative

CPI 169, CPI 169 racemate, CPI169, CPI-169, CPI169 racemate, CPI-169 racemate, EZH1, EZH2 WT, EZH2 Y641N, Epigenetic Reader Domain, EpigeneticReaderDomain, Histone Methyltransferase, HistoneMethyltransferase

Field of Research

Epigenetics & Chromatin

Purity

99.14% (May vary between batches)

Solubility

Ethanol:93 mg/mL (175.92 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:93 mg/mL (175.92 mM)

Smiles

CCS (=O) (=O) N1CCC (CC1) C (C) n1c (C) c (C (=O) NCc2c (OC) cc (C) [nH]c2=O) c2ccccc12

Molecular Formula

C27H36N4O5S

Molecular Weight

528.66

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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