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CPI-637

CPI-637 is a cell-permeable benzodiazepinone compound that acts as a selective inhibitor of the CBP and EP300 bromodomains. It is utilized in epigenetic research to probe the roles of these acetyl-lysine readers in cellular processes and has been applied in both in vitro biochemical assays and in vivo model studies.

Product Specifications

CAS Number

1884712-47-3

Product Name Alternative

CBP, BRD4, CPI-637, CPI637, CPI 637, Epigenetic Reader Domain, EpigeneticReaderDomain, EP300, HistoneAcetyltransferase, Histone Acetyltransferase, HAT, HATs, Inhibitor, inhibit

Field of Research

Epigenetics & Chromatin

Purity

99.75% (May vary between batches)

Solubility

Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:3.87 mg/mL (10.01 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)

Smiles

C[C@@H]1CC (=O) Nc2cccc (-c3ccc4n (C) nc (-c5cnn (C) c5) c4c3) c2N1

Molecular Formula

C22H22N6O

Molecular Weight

386.45

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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