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HS-1371

HS-1371 is a potent and selective small molecule inhibitor of RIP3 kinase, demonstrating an IC50 of 20.8 nM. It is a valuable research tool for investigating necroptosis in vitro and has been utilized in preclinical in vivo models to study inflammatory and ischemic diseases.

Product Specifications

CAS Number

2158197-70-5

Product Name Alternative

HS1371, HS-1371, HS 1371, inhibit, Inhibitor, Receptor-interacting protein kinases, RIPkinase, RIP3, RIPK, RIP kinase

Field of Research

Cell Biology, Signal Transduction

Purity

95.20% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.6 mM) ; DMSO:16.67 mg/mL (43.36 mM)

Smiles

Cc1ccc (Oc2ccnc3cc (ccc23) -c2cnn (c2) C2CCNCC2) cc1

Molecular Formula

C24H24N4O

Molecular Weight

384.47

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

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