HS-1371
HS-1371 is a potent and selective small molecule inhibitor of RIP3 kinase, demonstrating an IC50 of 20.8 nM. It is a valuable research tool for investigating necroptosis in vitro and has been utilized in preclinical in vivo models to study inflammatory and ischemic diseases.
Product Specifications
CAS Number
2158197-70-5
Product Name Alternative
HS1371, HS-1371, HS 1371, inhibit, Inhibitor, Receptor-interacting protein kinases, RIPkinase, RIP3, RIPK, RIP kinase
Field of Research
Cell Biology, Signal Transduction
Purity
95.20% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (2.6 mM) ; DMSO:16.67 mg/mL (43.36 mM)
Smiles
Cc1ccc (Oc2ccnc3cc (ccc23) -c2cnn (c2) C2CCNCC2) cc1
Molecular Formula
C24H24N4O
Molecular Weight
384.47
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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