DASA-58

DASA-58 is a potent and selective small molecule activator of the Pyruvate Kinase M2 (PKM2) isoform. Its application in research includes studying cancer metabolism, where PKM2 modulation is explored in both cellular and animal models to investigate tumor growth and metabolic reprogramming.

Product Specifications

CAS Number

1203494-49-8

Product Name Alternative

PKM2, Pyruvate Kinase, pyruvate kinase M2, TXNIP, inhibit, Inhibitor, glycolysis, AMPK, cancer metabolism, breast cancer, DASA 58, DASA58, DASA-58

Field of Research

Metabolism Research

Purity

96.96% (May vary between batches)

Solubility

10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.28 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:125.5 mg/mL (276.72 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble)