DEL-22379
DEL-22379 is a cell-permeable, water-soluble small molecule that potently inhibits ERK dimerization with an IC50 of approximately 0.5 μM. It is a valuable research tool for studying MAPK/ERK signaling in cancer models, applicable in both cellular and in vivo studies to investigate pathways driving tumor proliferation.
Product Specifications
CAS Number
181223-80-3
Product Name Alternative
DEL 22379, DEL22379, DEL-22379, Apoptosis, Inhibitor, inhibit, ERK, Extracellular signal regulated kinases
Field of Research
Cell Biology, Signal Transduction
Purity
99.30% (May vary between batches)
Solubility
DMSO:22.2 mg/mL (49.94 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.5 mM)
Smiles
COc1ccc2[nH]cc (C=C3C (=O) Nc4ccc (NC (=O) CCN5CCCCC5) cc34) c2c1
Molecular Formula
C26H28N4O3
Molecular Weight
444.53
Storage Conditions
-20°C
Notes
For research use only.
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