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ZL0420

ZL0420 is a potent and selective BRD4 inhibitor, demonstrating nanomolar affinity with IC50 values of 27 nM for BD1 and 32 nM for BD2. This small molecule is a valuable chemical probe for epigenetic research, enabling the study of BRD4 function in oncology and inflammation models both in vitro and in vivo.

Product Specifications

CAS Number

2229039-45-4

Product Name Alternative

BRD4, BET, bromodomains, (E/Z) -ZL0420, airway inflammation, Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor, immune response genes, inhibit, ZL0420, ZL-0420, ZL 0420

Field of Research

Epigenetics & Chromatin

Purity

97.77% (May vary between batches)

Solubility

DMSO:59 mg/mL (199.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.75 mM)

Smiles

Cc1cc (\N=N\c2ccc3NC (=O) CCc3c2) c (N) cc1O

Molecular Formula

C16H16N4O2

Molecular Weight

296.32

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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