ZL0420
ZL0420 is a potent and selective BRD4 inhibitor, demonstrating nanomolar affinity with IC50 values of 27 nM for BD1 and 32 nM for BD2. This small molecule is a valuable chemical probe for epigenetic research, enabling the study of BRD4 function in oncology and inflammation models both in vitro and in vivo.
Product Specifications
CAS Number
2229039-45-4
Product Name Alternative
BRD4, BET, bromodomains, (E/Z) -ZL0420, airway inflammation, Epigenetic Reader Domain, EpigeneticReaderDomain, Inhibitor, immune response genes, inhibit, ZL0420, ZL-0420, ZL 0420
Field of Research
Epigenetics & Chromatin
Purity
97.77% (May vary between batches)
Solubility
DMSO:59 mg/mL (199.11 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (6.75 mM)
Smiles
Cc1cc (\N=N\c2ccc3NC (=O) CCc3c2) c (N) cc1O
Molecular Formula
C16H16N4O2
Molecular Weight
296.32
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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