Epoxomicin
Epoxomicin is a potent and selective proteasome inhibitor that primarily targets the chymotrypsin-like (CH-L) activity of the 20S proteasome. It is widely used in research to study proteasome function, protein degradation pathways, and has demonstrated anti-inflammatory and anti-cancer effects in both cellular and animal models.
Product Specifications
CAS Number
134381-21-8
Product Name Alternative
Covalently, cytotoxicities, BBB, BU-4061T, Apoptosis, 20S proteasome, Epoxomicin, Epoxyketone-containing, Proteasome
Field of Research
Protein Biochemistry, Stem Cell & Developmental Biology
Purity
>98%
Bioactivity
Irreversible 20S proteasome inhibitor
Form
Lyophilized
Solubility
Soluble in DMSO (up to 10 mg/ml) .
Smiles
CC[C@H] (C) [C@H] (NC (=O) [C@H] ([C@@H] (C) CC) N (C) C (C) =O) C (=O) N[C@@H] ([C@@H] (C) O) C (=O) N[C@@H] (CC (C) C) C (=O) [C@@]1 (C) CO1
Molecular Formula
C28H50N4O7
Molecular Weight
554.73
Storage Conditions
-20°C
Notes
For research use only.
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