FRAX486 HCL (1232030-35-1 free base)

FRAX486 hydrochloride is a potent and selective p21-activated kinase (PAK) inhibitor, demonstrating IC50 values of 14 nM for PAK1, 33 nM for PAK2, 39 nM for PAK3, and 575 nM for PAK4. This small molecule is a valuable research tool for studying PAK signaling in cancer cell proliferation, neuronal morphology, and other cellular processes in both in vitro and in vivo models.