FRAX486 HCL (1232030-35-1 free base)
FRAX486 hydrochloride is a potent and selective p21-activated kinase (PAK) inhibitor, demonstrating IC50 values of 14 nM for PAK1, 33 nM for PAK2, 39 nM for PAK3, and 575 nM for PAK4. This small molecule is a valuable research tool for studying PAK signaling in cancer cell proliferation, neuronal morphology, and other cellular processes in both in vitro and in vivo models.
Product Specifications
Product Name Alternative
PAK4, PAK3, PAK2, PAK1, FRAX486 HCL (1232030 35 1 free base), FRAX486 HCL (1232030351 free base), FRAX-486 HCL (1232030-35-1 free base), FRAX486 HCL (1232030-35-1 free base)
Field of Research
Signal Transduction
Purity
98.85% (May vary between batches)
Solubility
DMSO:10.3 mg/mL (18.73 mM)
Smiles
FC1=CC (NC2=NC=C3C (N (C (C (C4=CC=C (C=C4Cl) Cl) =C3) =O) CC) =N2) =CC=C1N5CCNCC5.[H]Cl
Molecular Formula
C25H24Cl3FN6O
Molecular Weight
549.86
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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