Fumagillin
Fumagillin (Amebacilin) is an irreversible and selective inhibitor of Methionine Aminopeptidase 2 (MetAP2) . It is employed as an antibiotic against microsporidiosis and serves as a key research tool in studying angiogenesis, tumor growth, and obesity in both in vitro and in vivo models.
Product Specifications
CAS Number
23110-15-8
Product Name Alternative
Antibiotic, Amebacilin, NSC 9168, inhibit, NSC9168, NSC-9168, Parasite, MetAP2, Inhibitor, HIV, HIV Protease, HIVProtease, Human immunodeficiency virus, Fumagillin
Field of Research
Cardiovascular Research
Purity
>98%
Bioactivity
MetAP-2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml) .
Smiles
[H][C@@]1 ([C@H] (OC) [C@@H] (CC[C@]11CO1) OC (=O) \C=C\C=C\C=C\C=C\C (O) =O) [C@@]1 (C) O[C@@H]1CC=C (C) C
Molecular Formula
C26H34O7
Molecular Weight
458.54
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
(2E,4E,6E,8E) -Mono[ (3R,4S,5S,6R) -5-methoxy-4-[ (2R,3R) -2-methyl-3- (3-methyl-2-butenyl) oxiranyl]-1- oxaspiro[2.5]oct-6-yl] 2,4,6,8-decatetraenedioic acid ester
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