GSK481
GSK481 is a potent and selective small molecule inhibitor of RIP1 kinase (RIPK1) . It is a valuable research tool for investigating necroptosis in cellular and animal models, aiding the study of inflammatory and degenerative diseases.
Product Specifications
CAS Number
1622849-58-4
Product Name Alternative
Inhibit, Inhibitor, GSK481, GSK'481, GSK-481, GSK 481, RIP kinase, RIPK, RIP1, RIPkinase, Receptor-interacting protein kinases
Field of Research
Cell Biology, Signal Transduction
Purity
98.97% (May vary between batches)
Solubility
DMSO:70 mg/mL (185.48 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.3 mM)
Smiles
CN1c2ccccc2OC[C@H] (NC (=O) c2cc (Cc3ccccc3) on2) C1=O
Molecular Formula
C21H19N3O4
Molecular Weight
377.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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