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HA15

HA15 is a selective BiP/GRP78 inhibitor with demonstrated anti-cancer activity against melanoma, including patient-derived and therapy-resistant cells. It has shown efficacy in both in vitro cell culture and in vivo xenograft models, making it a valuable research tool for studying ER stress and oncology.

Product Specifications

CAS Number

1609402-14-3

Product Name Alternative

Autophagy, Apoptosis, BiP, inhibit, HSP, HA 15, HA15, HA-15, HSPA5, GRP78, Inhibitor, Heat shock proteins

Field of Research

Cell Biology, Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Purity

98.00% (May vary between batches)

Solubility

DMSO:115 mg/mL (246.47 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (7.07 mM) ; Ethanol:42 mg/mL (90.02 mM)

Smiles

CN (C) c1cccc2c (cccc12) S (=O) (=O) Nc1cccc (c1) -c1csc (NC (C) =O) n1

Molecular Formula

C23H22N4O3S2

Molecular Weight

466.58

Storage Conditions

-20°C

Notes

For research use only.

Available Sizes

Frequently Asked Questions

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