Ixabepilone
Ixabepilone is an orally available microtubule-stabilizing agent that binds tubulin, inducing polymerization, G2-M phase arrest, and apoptosis. It is widely used in cancer research, demonstrating activity in both in vitro cell-based assays and in vivo tumor models for studying chemotherapeutic mechanisms.
Product Specifications
CAS Number
219989-84-1
Product Name Alternative
Apoptosis, Azaepothilone B, Aza-epothilone B, BMS 247550, BMS 247550-1, BMS247550, BMS-247550, Ixempra, Ixabepilone, inhibit, Inhibitor, MicrotubuleAssociated, Microtubule Associated, Microtubule/Tubulin
Field of Research
Cell Biology, Infectious Disease & Virology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:250 mg/mL (493.39 mM) ; Ethanol:93 mg/mL (183.54 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:3.3 mg/mL (6.51 mM)
Smiles
C[C@H]1CCC[C@@]2 (C) O[C@H]2C[C@H] (NC (=O) C[C@H] (O) C (C) (C) C (=O) [C@H] (C) [C@H]1O) C (\C) =C\c1csc (C) n1
Molecular Formula
C27H42N2O5S
Molecular Weight
506.7
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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