Quisinostat dihydrochloride
Quisinostat dihydrochloride is a potent and selective second-generation HDAC inhibitor, showing highest activity against HDAC1. It has been investigated in Phase 2 clinical trials for oncology research, with studies demonstrating its effects on cancer cell proliferation and apoptosis in both cellular and animal models.
Product Specifications
CAS Number
875320-31-3
Product Name Alternative
Apoptosis, Autophagy, deacetylase, Inhibitor, HDAC, HDAC2, HDAC10, HDAC11, HDAC1, HDAC4, hematologic, histone, Histone deacetylases, malignancies, JNJ26854165 (Quisinostat), JNJ26854165 (Quisinostat) 2HCl, JNJ26481585, JNJ-26481585, JNJ-26481585 2HCl, inhibit, JNJ 26481585, Quisinostat, Quisinostat (JNJ-26481585), Quisinostat (JNJ-26481585) 2HCl, Quisinostat 2HCl, Quisinostat dihydrochloride, Quisinostat Dihydrochloride
Field of Research
Cell Biology, Epigenetics & Chromatin, Molecular Biology
Purity
97.13% (May vary between batches)
Solubility
10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.28 mM) ; DMSO:73 mg/mL (156.19 mM) ; Ethanol:< 1 mg/mL (insoluble or slightly soluble) ; H2O:< 1 mg/mL (insoluble or slightly soluble)
Smiles
Cl.Cl.Cn1cc (CNCC2CCN (CC2) c2ncc (cn2) C (=O) NO) c2ccccc12
Molecular Formula
C21H28Cl2N6O2
Molecular Weight
467.39
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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