Belumosudil
Belumosudil (Rezurock) is a selective, orally bioavailable ROCK2 inhibitor with an IC50 of 60 nM. It is a research tool for studying Rho-kinase signaling in fibrotic diseases, with applications in both in vitro biochemical assays and in vivo models of chronic graft-versus-host disease.
Product Specifications
CAS Number
911417-87-3
Product Name Alternative
KD025; SLx-2119
Field of Research
Cardiovascular Research, Immunology & Inflammation
Purity
>98%
Bioactivity
ROCK2 inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 25 mg/ml)
Smiles
CC (C) NC (=O) COc1cccc (c1) -c1nc (Nc2ccc3[nH]ncc3c2) c2ccccc2n1
Molecular Formula
C26H24N6O2
Molecular Weight
452.5
Storage Conditions
-20°C
Notes
For research use only.
Other Product Names
2-[3-[4- (1H-Indazol-5-yl) amino) quinazolin-2-yl]phenoxy]-N-propan-2-ylacetamide
Available Sizes
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