LJH685
LJH685 is a potent and selective pan-RSK inhibitor, exhibiting IC50 values of 6, 5, and 4 nM against RSK1, RSK2, and RSK3, respectively. This small molecule is a valuable research tool for studying RSK signaling in cancer cell proliferation and survival, with applications in both in vitro and in vivo models.
Product Specifications
CAS Number
1627710-50-2
Product Name Alternative
Inhibitor, LJH 685, LJH685, LJH-685, inhibit, Apoptosis, Ribosomal S6 Kinase (RSK), RSK1, RSK3, RSK2, S6 Kinase, S6K, S6Kinase
Field of Research
Cell Biology, Signal Transduction
Purity
98.00% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; DMSO:71 mg/mL (186.15 mM) ; Ethanol:16 mg/mL (41.95 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.24 mM)
Smiles
CN1CCN (CC1) c1ccc (cc1) -c1ccncc1-c1cc (F) c (O) c (F) c1
Molecular Formula
C22H21F2N3O
Molecular Weight
381.42
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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