LJI308
LJI308 is a potent and pan-RSK inhibitor, exhibiting IC50 values of 6 nM (RSK1), 4 nM (RSK2), and 13 nM (RSK3) . This small molecule is a valuable research tool for studying RSK signaling in cancer cell proliferation and survival, with applications in both in vitro and in vivo experimental models.
Product Specifications
CAS Number
1627709-94-7
Product Name Alternative
Cancer, breaks, double-strand, Inhibitor, LJI 308, LJI308, LJI-308, mutation, inhibit, phosphorylation, stimulation, RSK1, RSK2, RSK3, S6 Kinase, S6K, S6Kinase, Ribosomal S6 Kinase (RSK), viability
Field of Research
Cell Biology, Signal Transduction
Purity
98.86% (May vary between batches)
Solubility
10% DMSO+90% Corn Oil:2.5 mg/mL (6.79 mM) ; H2O:Insoluble; DMSO:50 mg/mL (135.73 mM)
Smiles
Oc1c (F) cc (cc1F) -c1cnccc1-c1ccc (cc1) N1CCOCC1
Molecular Formula
C21H18F2N2O2
Molecular Weight
368.38
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
Frequently Asked Questions
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