Larotrectinib sulfate
Larotrectinib sulfate is a potent, orally bioavailable, and selective inhibitor of the tropomyosin receptor kinase (TRK) family. It is widely used in preclinical research to investigate TRK-driven cancers, demonstrating efficacy in both in vitro cellular assays and in vivo tumor models.
Product Specifications
CAS Number
1223405-08-0
Product Name Alternative
Apoptosis, ARRY 470, ARRY470, ARRY-470 (sulfate), LOXO-101, LOXO101, LOXO 101 Sulfate, LOXO 101, LOXO-101 (sulfate), LOXO101 Sulfate, LOXO-101 sulfate, Trk receptor, Trk Receptor, Trk, Trkreceptor, Tropomyosin related kinase receptor
Field of Research
Cell Biology, Pharmacology & Drug Discovery, Signal Transduction
Purity
98.62% (May vary between batches)
Solubility
DMSO:50 mg/mL (94.96 mM) ; Ethanol:10 mg/mL (18.99 mM) ; H2O:< 1 mg/mL (insoluble or slightly soluble) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2.5 mg/mL (4.75 mM)
Smiles
OS (O) (=O) =O.O[C@H]1CCN (C1) C (=O) Nc1cnn2ccc (nc12) N1CCC[C@@H]1c1cc (F) ccc1F
Molecular Formula
C21H22F2N6O2·H2O4S
Molecular Weight
526.51
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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