Samotolisib
Samotolisib (LY3023414) is an orally bioavailable, ATP-competitive inhibitor targeting class I PI3K isoforms, DNA-PK, and mTOR. It has been investigated in preclinical and clinical studies for various solid tumors, including advanced breast and colon cancers, demonstrating research utility in both in vitro and in vivo models.
Product Specifications
CAS Number
1386874-06-1
Product Name Alternative
Autophagy, DNA-dependent protein kinase, DNAPK, DNA-PK, class I PI3K isoforms, Mammalian target of Rapamycin, GTPL 8918, GTPL8918, GTPL-8918, Inhibitor, inhibit, mTOR kinase, mTOR, LY 3023414, LY3023414, LY-3023414, PI3K, Phosphoinositide 3-kinase, Samotolisib
Field of Research
Cell Biology, Molecular Biology, Signal Transduction
Purity
98.41% (May vary between batches)
Solubility
H2O:< 1 mg/mL (insoluble or slightly soluble) ; Ethanol:57 mg/mL (140.23 mM) ;10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.92 mM) ; DMSO:50 mg/mL (123.01 mM)
Smiles
COC (C) Cn1c2c (cnc3ccc (cc23) -c2cncc (c2) C (C) (C) O) n (C) c1=O
Molecular Formula
C23H26N4O3
Molecular Weight
406.48
Storage Conditions
-20°C
Notes
For research use only.
Available Sizes
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