MK-886
MK-886 (L 663536) is a small molecule that acts as a dual-function agent, primarily known as a 5-lipoxygenase-activating protein (FLAP) inhibitor that blocks leukotriene biosynthesis. It also serves as a moderate PPARα antagonist. This compound has been utilized in research exploring inflammation, asthma, and metabolic diseases in both cellular and animal models.
Product Specifications
CAS Number
118414-82-7
Product Name Alternative
L-663,536
Field of Research
Immunology & Inflammation
Purity
>98%
Bioactivity
5-Lipoxygenase activating protein (FLAP) inhibitor
Form
Powder
Solubility
Soluble in DMSO (up to 40 mg/ml) .
Smiles
CC (C) c1ccc2n (Cc3ccc (Cl) cc3) c (CC (C) (C) C (O) =O) c (SC (C) (C) C) c2c1
Molecular Formula
C27H34ClNO2S
Molecular Weight
472.1
Storage Conditions
RT
Notes
For research use only.
Other Product Names
3-[1- (4-chlorobenzyl) -3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid
Available Sizes
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