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MK-886

MK-886 (L 663536) is a small molecule that acts as a dual-function agent, primarily known as a 5-lipoxygenase-activating protein (FLAP) inhibitor that blocks leukotriene biosynthesis. It also serves as a moderate PPARα antagonist. This compound has been utilized in research exploring inflammation, asthma, and metabolic diseases in both cellular and animal models.

Product Specifications

CAS Number

118414-82-7

Product Name Alternative

L-663,536

Field of Research

Immunology & Inflammation

Purity

>98%

Bioactivity

5-Lipoxygenase activating protein (FLAP) inhibitor

Form

Powder

Solubility

Soluble in DMSO (up to 40 mg/ml) .

Smiles

CC (C) c1ccc2n (Cc3ccc (Cl) cc3) c (CC (C) (C) C (O) =O) c (SC (C) (C) C) c2c1

Molecular Formula

C27H34ClNO2S

Molecular Weight

472.1

Storage Conditions

RT

Notes

For research use only.

Other Product Names

3-[1- (4-chlorobenzyl) -3-t-butyl-thio-5-isopropylindol-2-yl]-2,2-dimethylpropanoic acid

Available Sizes

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